• Science

Genomes 3


Author: Terence A. Brown
Publisher: Garland Science
ISBN: 0815341385
Category: Science
Page: 713
View: 9596
The VitalBook e-book version of Genomes 3 is only available in the US and Canada at the present time. To purchase or rent please visit http://store.vitalsource.com/show/9780815341383 Covering molecular genetics from the basics through to genome expression and molecular phylogenetics, Genomes 3is the latest edition of this pioneering textbook. Updated to incorporate the recent major advances, Genomes 3 is an invaluable companion for any undergraduate throughout their studies in molecular genetics. Genomes 3 builds on the achievements of the previous two editions by putting genomes, rather than genes, at the centre of molecular genetics teaching. Recognizing that molecular biology research was being driven more by genome sequencing and functional analysis than by research into genes, this approach has gathered momentum in recent years.

    • Science

Genomes 3


Author: Terence A. Brown
Publisher: Garland Science
ISBN: 0815341385
Category: Science
Page: 713
View: 474
The VitalBook e-book version of Genomes 3 is only available in the US and Canada at the present time. To purchase or rent please visit http://store.vitalsource.com/show/9780815341383 Covering molecular genetics from the basics through to genome expression and molecular phylogenetics, Genomes 3is the latest edition of this pioneering textbook. Updated to incorporate the recent major advances, Genomes 3 is an invaluable companion for any undergraduate throughout their studies in molecular genetics. Genomes 3 builds on the achievements of the previous two editions by putting genomes, rather than genes, at the centre of molecular genetics teaching. Recognizing that molecular biology research was being driven more by genome sequencing and functional analysis than by research into genes, this approach has gathered momentum in recent years.

    • Science

Genomes


Author: T.A. Brown
Publisher: Garland Science
ISBN: 1136969969
Category: Science
Page: 736
View: 4817
Covering molecular genetics from the basics through to genome expression and molecular phylogenetics, Genomes 3 is the latest edition of this pioneering textbook. Newly updated to incorporate the recent major advances, Genomes 3 is an invaluable companion for any undergraduate throughout their studies in molecular genetics. Following extensive reviewing, the new edition has been significantly restructured. The single chapter on genome anatomies has been expanded into three chapters to incorporate the latest sequencing achievements. An additional chapter on understanding genome expression has also been included, while the chapters on studying genomes have been brought to the front of the book to align it more closely to the practical reality of molecular genetics tuition. The end-of-chapter exercises have been overhauled and extended to give students and lecturers a much wider range of tests and challenges. Multiple choice questions have been included for the first time and an innovative figure test has been introduced to test readers' visual understanding.

    • Science

Genomes


Author: T. A. Brown,Terence A. Brown
Publisher: N.A
ISBN: 9780815345084
Category: Science
Page: 524
View: 2412
Preceded by: Genomes 3 / T. A. Brown. 3rd ed. New York: Garland Science, c2007.

Introduction to Genomics


Author: Arthur Lesk
Publisher: Oxford University Press
ISBN: 0198754833
Category:
Page: 544
View: 1075
Our genome is the blueprint for our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism. Yet it is more than a static information store: our genome is a dynamic, tightly-regulated collection of genes, which switch on andoff in many combinations to give the variety of cells from which our bodies are formed. But how do we identify the genes that make up our genome? How do we determine their function? And how do different genes form the regulatory networks that direct the processes of life? Introduction to Genomics is the most up-to-date and complete textbook for students approaching the subject for the first time. Lesk's engaging writing style brings a narrative to a disparate field of study and offers a fascinating insight into what can be revealed from the study of genomes. The bookcovers: the similarities and differences between organisms; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing. The Online Resource Centre accompanying Introduction to Genomics features: For students: * Extensive and imaginative weblems (web-based problems) for each chapter designed to give you practice with the tools required for further study and research in the field* Hints and answers to end-of-chapter problems and exercises support your self-directed learning* Guided tour of websites and major archival databanks in genomics offer a wealth of resources to springboard your own research * Journal club: links to related research articles on topics covered in the book are paired with engaging questions to improve your interpretation of the primary literature* Rotating figures allow you to visualize complex structuresFor registered adopters: * Downloadable figures from the book.

    • Science

From Genes to Genomes

Concepts and Applications of DNA Technology
Author: Jeremy W. Dale,Malcolm von Schantz,Nicholas Plant
Publisher: John Wiley & Sons
ISBN: 1119954274
Category: Science
Page: 408
View: 2753
The latest edition of this highly successful textbook introduces the key techniques and concepts involved in cloning genes and in studying their expression and variation. The new edition features: Increased coverage of whole-genome sequencing technologies and enhanced treatment of bioinformatics. Clear, two-colour diagrams throughout. A dedicated website including all figures. Noted for its outstanding balance between clarity of coverage and level of detail, this book provides an excellent introduction to the fast moving world of molecular genetics.

    • Science

Genome

The Autobiography of a Species in 23 Chapters
Author: Matt Ridley
Publisher: Harper Collins
ISBN: 0062253468
Category: Science
Page: 368
View: 5499
The genome's been mapped. But what does it mean? Arguably the most significant scientific discovery of the new century, the mapping of the twenty-three pairs of chromosomes that make up the human genome raises almost as many questions as it answers. Questions that will profoundly impact the way we think about disease, about longevity, and about free will. Questions that will affect the rest of your life. Genome offers extraordinary insight into the ramifications of this incredible breakthrough. By picking one newly discovered gene from each pair of chromosomes and telling its story, Matt Ridley recounts the history of our species and its ancestors from the dawn of life to the brink of future medicine. From Huntington's disease to cancer, from the applications of gene therapy to the horrors of eugenics, Matt Ridley probes the scientific, philosophical, and moral issues arising as a result of the mapping of the genome. It will help you understand what this scientific milestone means for you, for your children, and for humankind.

    • Science

Plant Genes, Genomes and Genetics


Author: Erich Grotewold,Elizabeth Kellogg,Joseph Chappell
Publisher: John Wiley & Sons
ISBN: 1119998875
Category: Science
Page: 264
View: 5629
Plant Genes, Genomes and Genetics provides a dedicated, plant focused textbook for graduates and advanced undergraduates. The book considers the control of plant gene expression in the broad sense from the mechanism of transcription to the generation of a protein and will provide a general idea of how these processes occur in plants, specifically highlighting cases when plants and other organisms are different. Plant gene expression continues to be taught from general textbooks that focus primarily on yeast and animals for eukaryotes, yet rarely mention plants so this book aims to fill that gap in teaching material. This book will be the first book in the Wiley-Blackwell/ASPB Plant Biology Book Series.

    • Science

Molecular Biology of the Cell


Author: Bruce Alberts
Publisher: Garland Science
ISBN: 1317563743
Category: Science
Page: 1464
View: 5904
As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.

    • Mathematics

Introduction to Computational Biology

Maps, Sequences and Genomes
Author: Michael S. Waterman
Publisher: CRC Press
ISBN: 1351437089
Category: Mathematics
Page: 448
View: 6627
Biology is in the midst of a era yielding many significant discoveries and promising many more. Unique to this era is the exponential growth in the size of information-packed databases. Inspired by a pressing need to analyze that data, Introduction to Computational Biology explores a new area of expertise that emerged from this fertile field- the combination of biological and information sciences. This introduction describes the mathematical structure of biological data, especially from sequences and chromosomes. After a brief survey of molecular biology, it studies restriction maps of DNA, rough landmark maps of the underlying sequences, and clones and clone maps. It examines problems associated with reading DNA sequences and comparing sequences to finding common patterns. The author then considers that statistics of pattern counts in sequences, RNA secondary structure, and the inference of evolutionary history of related sequences. Introduction to Computational Biology exposes the reader to the fascinating structure of biological data and explains how to treat related combinatorial and statistical problems. Written to describe mathematical formulation and development, this book helps set the stage for even more, truly interdisciplinary work in biology.

    • Computers

Computational Genome Analysis

An Introduction
Author: Richard C. Deonier,Simon Tavaré,Michael Waterman
Publisher: Springer Science & Business Media
ISBN: 9780387987859
Category: Computers
Page: 535
View: 676
This book presents the foundations of key problems in computational molecular biology and bioinformatics. It focuses on computational and statistical principles applied to genomes, and introduces the mathematics and statistics that are crucial for understanding these applications. The book features a free download of the R software statistics package and the text provides great crossover material that is interesting and accessible to students in biology, mathematics, statistics and computer science. More than 100 illustrations and diagrams reinforce concepts and present key results from the primary literature. Exercises are given at the end of chapters.

    • Science

Genetics

Genes, Genomes, and Evolution
Author: Philip Meneely,Rachel Dawes Hoang,Katherine Heston,Iruka N. Okeke
Publisher: Oxford University Press
ISBN: 019879536X
Category: Science
Page: 740
View: 8576
Recent advances that allow scientists to quickly and accurately sequence a genome have revolutionized our view of the structure and function of genes as well as our understanding of evolution. A new era of genetics is underway, one that allows us to fully embrace Dobzhansky's famous statement that "Nothing in biology makes sense except in the light of evolution". Genetics: Genes, Genomes, and Evolution presents the fundamental principles of genetics and molecular biology from an evolutionary perspective as informed by genome analysis. By using what has been learned from the analyses of bacterial and eukaryotic genomes as its basis, the book unites evolution, genomics, and genetics in one narrative approach. Genomic analysis is inherently both molecular and evolutionary, and every chapter is approached from this unified perspective. Similarly, genomic studies have provided a deeper appreciation of the profound relationships between all organisms - something reflected in the book's integrated discussion of bacterial and eukaryotic evolution, genetics and genomics. It is an approach that provides students with a uniquely flexible and contemporary view of genetics, genomics, and evolution. Online Resource Centre: - Video tutorials: a series of videos that provide deeper, step-by-step explanations of a range of topics featured in the text. - Flashcards: electronic flashcards covering the key terms from the text. For registered adopters of the text: - Digital image library: Includes electronic files in PowerPoint format of every illustration, photo, graph and table from the text - Lecture notes: Editable lecture notes in PowerPoint format for each chapter help make preparing lectures faster and easier than ever. Each chapter's presentation includes a succinct outline of key concepts, and incorporates the graphics from the chapter - Library of exam-style questions: a suite of questions from which you can pick potential assignments and exams. - Test bank of multiple-choice questions: a ready-made electronic testing resource that can be customized by lecturers and delivered via their institution's virtual learning environment. - Solutions to all questions featured in the book: solutions written by the authors help make the grading of homework assignments easier. - Journal Clubs: a series of questions that guide your students through the reading and interpretation of a research paper that relates to the subject matter of a given chapter. Each Journal club includes model answers for lecturers. - Instructor's guide: The instructor's guide discusses the educational approach taken by Genetics: Genes, Genomes, and Evolution in more detail, why this approach has been taken, what benefits it offers, and how it can be adopted in your class.

    • Medical

Animal Genomics for Animal Health

Paris, France, 25-27 October 2007
Author: Marie-Hélène Pinard
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805586191
Category: Medical
Page: 439
View: 1201
"It includes a review of the state of the art in animal genomics and its applications to animal health. The contributions describe the new tools available, such as HapMaps for chicken and cattle, and show how the understanding of gene structure and function can be successfully applied to delineate the molecular mechanisms of disease and determine complex phenotypes associated with health traits. A critical evaluation of future needs and future applications of animal genomics is also presented. The integration of animal genomics in animal health research is likely to revolutionize the way scientists approach the challenges of discovering highly effective drugs and vaccines for animal diseases."--BOOK JACKET.

    • Science

The Age of Genomes

Tales from the Front Lines of Genetic Medicine
Author: Steven Monroe Lipkin,Jon Luoma
Publisher: Beacon Press
ISBN: 0807074586
Category: Science
Page: 256
View: 6663
A leading geneticist explores what promises to be one of the most transformative advances in health and medicine in history Almost every week, another exciting headline appears about new advances in the field of genetics. Genetic testing is experiencing the kind of exponential growth once seen with the birth of the Internet, while the plummeting cost of DNA sequencing makes it increasingly accessible for individuals and families. Steven Lipkin and Jon Luoma posit that today’s genomics is like the last century’s nuclear physics: a powerful tool for good if used correctly, but potentially dangerous nonetheless. DNA testing is likely the most exciting advance in a long time for treating serious disease, but sequencing errors, complex biology, and problems properly interpreting genetic data can also cause life-threatening misdiagnoses of patients with debilitating and fatal genetic diseases. DNA testing can also lead to unnecessary procedures and significantly higher health-care costs. And just around the corner is the ability to cure genetic diseases using powerful gene-editing technologies that are already being used in human embryo research. Welcome to the Age of Genomes! The Age of Genomes immerses readers in true stories of patients on the frontier of genomic medicine and explores both the transformative potential and risks of genetic technology. It will inform anxious parents increasingly bombarded by offers of costly new prenatal testing products, and demonstrate how genetic technology, when deployed properly, can significantly improve the lives of patients who have devastating neurological diseases, cancer, and other maladies. Dr. Lipkin explains the science in depth, but in terms a layperson can follow.

    • Science

Neanderthal Man

In Search of Lost Genomes
Author: Svante PŠŠbo
Publisher: Basic Books (AZ)
ISBN: 0465020836
Category: Science
Page: 288
View: 9759
An influential geneticist traces his investigation into the genes of humanity's closest evolutionary relatives, explaining what his sequencing of the Neanderthal genome has revealed about their extinction and the origins of modern humans.

    • Science

The Human Genome


Author: Julia E. Richards,R. Scott Hawley
Publisher: Academic Press
ISBN: 9780080918655
Category: Science
Page: 420
View: 9403
Significant advances in our knowledge of genetics were made during the twentieth century but in the most recent decades, genetic research has dramatically increased its impact throughout society. Genetic issues are now playing a large role in health and public policy, and new knowledge in this field will continue to have significant implications for individuals and society. Written for the non-majors human genetics course, Human Genetics, 3E will increase the genetics knowledge of students who are learning about human genetics for the first time. This thorough revision of the best-selling Human Genome,2E includes entirely new chapters on forensics, stem cell biology, bioinformatics, and societal/ethical issues associated with the field. New special features boxes make connections between human genetics and human health and disease. Carefully crafted pedagogy includes chapter-opening case studies that set the stage for each chapter; concept statements interspersed throughout the chapter that keep first-time students focused on key concepts; and end-of-chapter questions and critical thinking activities. This new edition will contribute to creating a genetically literate student population that understands basic biological research, understands elements of the personal and health implications of genetics, and participates effectively in public policy issues involving genetic information . Includes topical material on forensics, disease studies, and the human genome project to engage non-specialist students Full, 4-color illustration program enhances and reinforces key concepts and themes Uniform organization of chapters includes interest boxes that focus on human health and disease, chapter-opening case studies, and concept statements to engage non-specialist readers

    • Science

Genomics and Personalized Medicine

What Everyone Needs to Know?
Author: Michael Snyder
Publisher: Oxford University Press
ISBN: 0190234784
Category: Science
Page: 240
View: 7615
In 2001 the Human Genome Project succeeded in mapping the DNA of humans. This landmark accomplishment launched the field of genomics, the integrated study of all the genes in the human body and the related biomedical interventions that can be tailored to benefit a person's health. Today genomics, part of a larger movement toward personalized medicine, is poised to revolutionize health care. By cross-referencing an individual's genetic sequence -- their genome -- against known elements of "Big Data," elements of genomics are already being incorporated on a widespread basis, including prenatal disease screening and targeted cancer treatments. With more innovations soon to arrive at the bedside, the promise of the genomics revolution is limitless. This entry in the What Everyone Needs to Know series offers an authoritative resource on the prospects and realities of genomics and personalized medicine. As this science continues to alter traditional medical paradigms, consumers are faced with additional options and more complicated decisions regarding their health care. This book provides the essential information everyone needs.

    • Science

Genes & Genomes

A Changing Perspective
Author: Maxine Singer,Paul Berg
Publisher: University Science Books
ISBN: 9780935702170
Category: Science
Page: 929
View: 8616
This overview of the molecular structures and mechanisms that underlie the utilization of genetic information by complex organisms emphasizes the experimental aspects of molecular genetics. It provides a complete introduction to both principles and methods.

    • Medical

Genome Stability

From Virus to Human Application
Author: Igor Kovalchuk,Olga Kovalchuk
Publisher: Academic Press
ISBN: 0128033452
Category: Medical
Page: 712
View: 4472
Every species has to preserve the integrity of its genome to ensure faithful passage of genetic information to the progeny. At the same time, there are times during the life of the organism and population in general when a fine balance in genome stability and diversification has to be made to benefit the survival of the species. Genome Stability teaches the reader how various species maintain this fine balance in genome stability and genome diversification in response to their environments. Genome Stability covers a wide range of topics, including the genome stability of DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes and mammals. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability as well as changes in genome stability in response to aging. Finally, Genome Stability covers how epigenetic factors contribute to genome stability and how the species pass the memory of the encounters to the progeny, thus influencing the genome of the progeny in an indirect manner. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly-expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability. Includes a collection of chapters on genome stability research from various kingdoms, including topics such as epigenetics and transgenerational effects Provides the first comprehensive coverage of the differences in the mechanisms utilized by different organisms to maintain genomic stability Contains applications of genome instability and its effect on human diseases Explains how various species maintain the fine balance in genome stability and genome diversification in response to their environments

    • Science

Genetics

From Genes to Genomes
Author: Leland Hartwell
Publisher: McGraw-Hill Higher Education
ISBN: 0077515099
Category: Science
Page: 816
View: 9666
Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The 5th edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between the early understanding of genetics and the new molecular discoveries that have changed the way the field of genetics is viewed.