• Science

Organic Chemistry: Principles and Mechanisms


Author: Joel Karty
Publisher: W. W. Norton
ISBN: 9780393919042
Category: Science
Page: 1308
View: 1663
Understanding over memorization. Joel Karty has dedicated nearly a decade developing a teaching approach and textbook that is organized by mechanism, promotes learning by doing, and provides students with the background and support they need to be successful in organic chemistry as well as pre-professional placement exams like the MCAT. Karty’s organization, conversational writing style, and interactive pedagogy facilitate understanding rather than memorization and place the emphasis back on mechanisms.

Organic Chemistry

Principles and Mechanisms
Author: Joel Karty
Publisher: N.A
ISBN: 9780393663556
Category:
Page: 1584
View: 7507

Organic Chemistry

Principles and Mechanisms
Author: Joel Karty
Publisher: W. W. Norton
ISBN: 9780393663549
Category:
Page: 1584
View: 9238
Organic chemistry can overwhelm students and force them to fall back on memorization. But once they understand how to use mechanisms, they can solve just about any problem. With an organization by mechanism, students will understand more, and memorize less. The Second Edition of this groundbreaking text provides a fresh, but proven approach to get students confident using mechanisms.Smartwork5 online homework supports learning by mirroring the text's organization and pedagogy. Students use an intuitive drawing tool while receiving instant hints and answer-specific feedback, making practice more productive.

    • Science

Organic Chemistry

Principles and Mechanisms
Author: Joel Karty
Publisher: W. W. Norton
ISBN: 9780393630749
Category: Science
Page: 1584
View: 6191
Organic chemistry can overwhelm students and force them to fall back on memorization. But once they understand how to use mechanisms, they can solve just about any problem. With an organization by mechanism, students will understand more, and memorize less. The Second Edition of this groundbreaking text provides a fresh, but proven approach to get students confident using mechanisms.Smartwork5 online homework supports learning by mirroring the text's organization and pedagogy. Students use an intuitive drawing tool while receiving instant hints and answer-specific feedback, making practice more productive.

    • Science

Study Guide and Solutions Manual

For Organic Chemistry: Principles and Mechanisms
Author: Joel Karty,Marie Melzer
Publisher: W W Norton & Company Incorporated
ISBN: 9780393922936
Category: Science
Page: 1117
View: 8013
Written by two dedicated teachers, this guide provides students with fully worked solutions to all unworked problems in the text. Every solution follows the Think/Solve format used in the textbook so the approach to problem-solving is modeled consistently. The Think step trains students to ask the right questions as they approach a problem, and the Solve step then walks them through the solution.

Organic Chemistry

Principles and Mechanisms
Author: Joel Karty
Publisher: W. W. Norton
ISBN: 9780393123616
Category:
Page: 1488
View: 7604
Joel Karty has dedicated nearly a decade developing a teaching approach and textbook that is organized by mechanism, promotes learning by doing, and provides students with the background and support they need to be successful in organic chemistry as well as pre-professional placement exams like the MCAT. Karty s organization, conversational writing style, and interactive pedagogy facilitate understanding rather than memorization and place the emphasis back on mechanisms."

    • Medical

The Organic Chemistry of Drug Design and Drug Action


Author: Richard B. Silverman,Mark W. Holladay
Publisher: Academic Press
ISBN: 0123820316
Category: Medical
Page: 536
View: 401
The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while including significant changes in format and coverage. This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries. Updates to all chapters, including new examples and references Chapter 1 (Introduction): Completely rewritten and expanded as an overview of topics discussed in detail throughout the book Chapter 2 (Lead Discovery and Lead Modification): Sections on sources of compounds for screening including library collections, virtual screening, and computational methods, as well as hit-to-lead and scaffold hopping; expanded sections on sources of lead compounds, fragment-based lead discovery, and molecular graphics; and deemphasized solid-phase synthesis and combinatorial chemistry Chapter 3 (Receptors): Drug-receptor interactions, cation-π and halogen bonding; atropisomers; case history of the insomnia drug suvorexant Chapter 4 (Enzymes): Expanded sections on enzyme catalysis in drug discovery and enzyme synthesis Chapter 5 (Enzyme Inhibition and Inactivation): New case histories: for competitive inhibition, the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib and Abelson kinase inhibitor, imatinib for transition state analogue inhibition, the purine nucleoside phosphorylase inhibitors, forodesine and DADMe-ImmH, as well as the mechanism of the multisubstrate analog inhibitor isoniazid for slow, tight-binding inhibition, the dipeptidyl peptidase-4 inhibitor, saxagliptin Chapter 7 (Drug Resistance and Drug Synergism): This new chapter includes topics taken from two chapters in the previous edition, with many new examples Chapter 8 (Drug Metabolism): Discussions of toxicophores and reactive metabolites Chapter 9 (Prodrugs and Drug Delivery Systems): Discussion of antibody–drug conjugates

    • Science

Practical Synthetic Organic Chemistry

Reactions, Principles, and Techniques
Author: Stéphane Caron
Publisher: John Wiley & Sons
ISBN: 1118093569
Category: Science
Page: 898
View: 9492
A hands-on guide to assist in the planning and execution of synthetic reactions in the laboratory Despite the maturity of organic chemistry, it can still be very challenging to identify optimal methods for synthetic transformations that perform as well in real-world manufacturing processes as they do in the laboratory. This detailed and accessible guide attempts to address this vexing issue and deliver proven methodologies practicing synthetic chemists will find valuable for identifying reaction conditions that work reliably over the broadest possible range of substrates. Practical Synthetic Organic Chemistry: Provides a practical guide to strategically planning and executing chemical syntheses for the bench chemist in industry Discusses information that is not common knowledge beyond the boundaries of process chemistry groups, such as the synthetic routes of selected contemporary pharmaceutical drugs and practical solvents, as well as green chemistry concepts Highlights key reactions, including substitutions, additions, eliminations, rearrangements, oxidations, and reductions Addresses basic principles, mechanisms, advantages and disadvantages of the methodology, and techniques for achieving laboratory success Incorporating such an extraordinary wealth of information on organic chemistry and its related fields into one complete volume distinguishes Practical Synthetic Organic Chemistry as an incomparable desktop reference for professionals—and an invaluable study aid for students.

    • Science

Writing Reaction Mechanisms in Organic Chemistry


Author: Audrey Miller,Philippa H. Solomon
Publisher: Academic Press
ISBN: 9780124967120
Category: Science
Page: 471
View: 9463
Writing Reaction Mechanisms in Organic Chemistry, Second Edition, is an invaluable guide to charting the movements of atoms and electrons in the reactions of organic molecules. Miller and Solomon illustrate that understanding organic reactions is based on applying general principles rather than the rote memorization of unrelated processes, and, in turn, emphasize that writing mechanisms is a practical method of applying knowledge of previously encountered reactions and reaction conditions to new reactions. Students and research chemists alike will find this book useful in providing a method of organizing and synthesizing an oftentimes overwhelming quantity of information into a set of general principles and guidelines for determining and describing organic reaction mechanisms. * Essential for those students who need to have mechanisms explained in greater detail than most organic chemistry textbooks provide. * Illustrated with hundreds of chemical structures * Extensively rewritten and reorganized to make the presentation and format even easier for students to use * Contains many problem sets and answers to all problems to help students work through general principles and applications * Appendixes have been added to this edition that contain easily referenced information on Lewis structures, symbols for chemical notation, and the relative acidities of common substances

    • Science

A Self-study Guide to the Principles of Organic Chemistry

Key Concepts, Reaction Mechanisms, and Practice Questions for the Beginner
Author: Jiben Roy
Publisher: Universal-Publishers
ISBN: 1612332617
Category: Science
Page: 260
View: 6635
A Self-Study Guide to the Principles of Organic Chemistry: Key Concepts, Reaction Mechanisms, and Practice Questions for the Beginner will help students new to organic chemistry grasp the key concepts of the subject quickly and easily, as well as build a strong foundation for future study. Starting with the definition of "atom," the author explains molecules, electronic configuration, bonding, hydrocarbons, polar reaction mechanisms, stereochemistry, reaction varieties, organic spectroscopy, aromaticity and aromatic reactions, biomolecules, organic polymers, and a synthetic approach to organic compounds. The over one hundred diagrams and charts contained in this volume will help students visualize the structures and bonds as they read the text, and make the logic of organic chemistry clear and easily understood. Each chapter ends with a list of frequently-asked questions and answers, followed by additional practice problems. Answers are included in the Appendix.

    • Science

Principles of Organic Chemistry


Author: Robert J. Ouellette,J. David Rawn
Publisher: Academic Press
ISBN: 0128026340
Category: Science
Page: 496
View: 816
Class-tested and thoughtfully designed for student engagement, Principles of Organic Chemistry provides the tools and foundations needed by students in a short course or one-semester class on the subject. This book does not dilute the material or rely on rote memorization. Rather, it focuses on the underlying principles in order to make accessible the science that underpins so much of our day-to-day lives, as well as present further study and practice in medical and scientific fields. This book provides context and structure for learning the fundamental principles of organic chemistry, enabling the reader to proceed from simple to complex examples in a systematic and logical way. Utilizing clear and consistently colored figures, Principles of Organic Chemistry begins by exploring the step-by-step processes (or mechanisms) by which reactions occur to create molecular structures. It then describes some of the many ways these reactions make new compounds, examined by functional groups and corresponding common reaction mechanisms. Throughout, this book includes biochemical and pharmaceutical examples with varying degrees of difficulty, with worked answers and without, as well as advanced topics in later chapters for optional coverage. Incorporates valuable and engaging applications of the content to biological and industrial uses Includes a wealth of useful figures and problems to support reader comprehension and study Provides a high quality chapter on stereochemistry as well as advanced topics such as synthetic polymers and spectroscopy for class customization

    • Science

Organic Chemistry


Author: Jonathan Clayden,Nick Greeves,Stuart Warren
Publisher: Oxford University Press
ISBN: 0199270295
Category: Science
Page: 1234
View: 6030
Rev. ed. of: Organic chemistry / Jonathan Clayden ... [et al.].

    • Science

Organic Chemistry

Structure, Mechanism, Synthesis
Author: J. David Rawn,Robert J. Ouellette
Publisher: Academic Press
ISBN: 0128128399
Category: Science
Page: 1056
View: 5196
Organic Chemistry: Structure, Mechanism, Synthesis, Second Edition, provides basic principles of this fascinating and challenging science, which lies at the interface of physical and biological sciences. Offering accessible language and engaging examples and illustrations, this valuable introduction for the in-depth chemistry course engages students and gives future and new scientists a new approach to understanding, rather than merely memorizing the key concepts underpinning this fundamental area. The book builds in a logical way from chemical bonding to resulting molecular structures, to the corresponding physical, chemical and biological properties of those molecules. The book explores how molecular structure determines reaction mechanisms, from the smallest to the largest molecules—which in turn determine strategies for organic synthesis. The book then describes the synthetic principles which extend to every aspect of synthesis, from drug design to the methods cells employ to synthesize the molecules of which they are made. These relationships form a continuous narrative throughout the book, in which principles logically evolve from one to the next, from the simplest to the most complex examples, with abundant connections between the theory and applications. Featuring in-book solutions and instructor PowerPoint slides, this Second Edition offers an updated and improved option for students in the two-semester course and for scientists who require a high quality introduction or refresher in the subject. Offers improvements for the two-semester course sequence and valuable updates including two new chapters on lipids and nucleic acids Features biochemistry and biological examples highlighted throughout the book, making the information relevant and engaging to readers of all backgrounds and interests Includes a valuable and highly-praised chapter on organometallic chemistry not found in other standard references

    • Science

March's Advanced Organic Chemistry

Reactions, Mechanisms, and Structure
Author: Michael B. Smith
Publisher: Wiley
ISBN: 9780470462591
Category: Science
Page: 2080
View: 3060
The new, revised and updated 7th edition of March’s Advanced Organic Chemistry clearly explains the theories and examples of organic chemistry, providing the most comprehensive resource about organic chemistry available. Readers are guided on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. The first five chapters deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Chapters 6 to 9 are concerned with general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation, and finally the relationship between structure and reactivity. The last 10 chapters cover the nature and the scope of organic reactions and their mechanisms. The 7th edition proves again it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Key features of the 7th edition: Every chapter has been updated with the most recent reaction information with references to both the primary and review literature New to the 7th edition: 5,500 references since the last edition, updates / rewrites of the retained sections, and an updated index in Appendix B Contains more than 1650 reactions and 20,000 valuable references to the primary literature Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds synthesized Guides the reader on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. Reviews of the previous edition: "...a favorite general organic chemistry text and an easy-to-use one-volume reference. We are confident that this book will remain a dominant reference and that it will reside on many chemists' personal bookshelves." –Journal of Medicinal Chemistry "Who can hope to be seriously accepted as a member of the organic chemistry community without being in possession of at least one edition of 'March'?" –Chemistry and Industry

    • Science

Organic Chemistry Concepts

An EFL Approach
Author: Gregory Roos,Cathryn Roos
Publisher: Academic Press
ISBN: 0128018097
Category: Science
Page: 236
View: 7191
Organic Chemistry Concepts: An EFL Approach provides an introductory overview of the subject, to enable the reader to understand many critical, experimental facts. Designed to cover a single-semester course or a needed review on the principles of Organic Chemistry, the book is written and organized for readers whose first language is not English. Approximately 80% of the words used are drawn from the list of the 2,000 most common English words; the remaining 20% includes necessary technical words, common chemistry terms, and well-known academic words (per the Academic Word List). The book has been class-tested internationally as well as with native English speakers, and differs from other introductory textbooks in the subject both in its coverage and organization, with a particular focus on common problem areas. Focused on a limited number of functional classes, Organic Chemistry Concepts: An EFL Approach introduces those organic compounds early in the book. Once readers have a foundation of the concepts and language of organic chemistry, they can build from that knowledge and work with relatively complex molecules, such as some natural product types covered in a later chapter. The book describes basic level reaction mechanisms when instructive, and illustrations throughout to emphasize the 3D nature of organic chemistry. The book includes multiple pedagogical features, such as chapter questions and useful appendices, to support reader comprehension. Covers all primary concepts in accessible language and pedagogical features, worked examples, glossary, chapter questions, illustrations, and useful summaries Builds a foundation of key material through a structured framework from which readers can expand their understanding Contains class-tested content written in a straightforward and accessible manner for non-native English speakers

    • Science

Get Ready for Organic Chemistry


Author: Joel Karty
Publisher: Prentice Hall
ISBN: 9780321774125
Category: Science
Page: 280
View: 347
Get Ready for Organic Chemistry takes a unique approach to preparing students for one of the most challenging courses in the undergraduate curriculum by emphasizing fundamental chemical concepts and helping students develop a productive mindset for studying Organic Chemistry. The Second Edition offers new learning tools within the text and online to further student understanding and promote retention of key Organic principles. Available for an online course through MasteringChemistry®, Get Ready for Organic Chemistry can also be discounted when packaged with Pearson Chemistry titles.


    • Science

Green Organic Chemistry

Strategies, Tools, and Laboratory Experiments
Author: Kenneth M. Doxsee,James E. Hutchison
Publisher: Brooks/Cole Publishing Company
ISBN: N.A
Category: Science
Page: 244
View: 4979
"This lab text describes the tools and strategies of green chemistry, and the lab experiments that allow investigation of organic chemistry concepts and techniques in a greener laboratory setting. Students acquire the tools to assess the health and environmental impacts of chemical processes and the strategies to improve develop new processes that are less harmful to human health and the environment. The curriculum introduces a number of state-of-the-art experiments and reduces reliance on expensive environmental controls, such as fume hoods."--Provided by publisher.

    • Chemistry, Organic

Organic Chemistry Principles in Context

A Story-telling Historical Approach
Author: Mark M. Green
Publisher: Sciencefromaway
ISBN: 9780615702711
Category: Chemistry, Organic
Page: 452
View: 9679
"Organic Chemistry Principles in Context: A Story Telling Historical Approach" takes a path that is a radical departure from the way all other textbooks of this subject are written. The principles of organic chemistry are discovered by investigation of the complex phenomena that arise from application of these principles, crossing the spectrum from the academic to the biological to the industrial. All the fundamental principles of organic chemistry normally presented in an undergraduate one year organic chemistry course are found in this book in the context of the stories and the people involved in their discovery. The students who have used this book have found it to be an attractive and effective method of learning organic chemistry. The teachers of the subject have found that the book enhances their own appreciation and love of the subject. The author of the book, Professor Mark M. Green, has organized a free access web site with a link to the answers to all of the problems at the end of every section of the book. In addition this web site, OrganicChemistryPrinciplesinContext.com, has links to explanatory video lectures made by Professor Green for each of the book's twelve chapters.