• Medical

The Gene

An Intimate History
Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
ISBN: 1476733538
Category: Medical
Page: 608
View: 7566
THE #1 NEW YORK TIMES BESTSELLER A New York Times Notable Book A Washington Post and Seattle Times Best Book of the Year From the Pulitzer Prize-winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).

    • Science

The Gene

An Intimate History
Author: Siddhartha Mukherjee
Publisher: Random House
ISBN: 144818116X
Category: Science
Page: 608
View: 8614
Selected as a Book of the Year by The New York Times, The Economist, Independent, Observer and Mail on Sunday THE NEW YORK TIMES NUMBER ONE BESTSELLER SHORTLISTED FOR THE WELLCOME BOOK PRIZE 2017 ‘Dramatic and precise... [A] thrilling and comprehensive account of what seems certain to be the most radical, controversial and, to borrow from the subtitle, intimate science of our time... He is a natural storyteller... A page-turner... Read this book and steel yourself for what comes next’ Bryan Appleyard, Sunday Times The Gene is the story of one of the most powerful and dangerous ideas in our history, from bestselling, prize-winning author Siddhartha Mukherjee. Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master-code that makes and defines humans, that governs our form and function. This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856 where a monk stumbles on the idea of a ‘unit of heredity’. It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes. Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

    • Literary Collections

The Gene

An Intimate History
Author: Siddhartha Mukherjee
Publisher: Penguin UK
ISBN: 9386057050
Category: Literary Collections
Page: 560
View: 3457
Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master-code that makes and defines humans, that governs our form and function. The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856, where a monk stumbles on the idea of a ‘unit of heredity’. It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. Above all, this is a story driven by human ingenuity and obsessive minds–from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes. This is an epic, moving history of a scientific idea being brought to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history–the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to ‘read’ and ‘write’ the human genome–unleashing the potential to change the fates and identities of our children. Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity–and a vision of both humanity’s past and future.

    • Family & Relationships

The Gene Machine

How Genetic Technologies Are Changing the Way We Have Kids--and the Kids We Have
Author: Bonnie Rochman
Publisher: Scientific American / Farrar, Straus and Giroux
ISBN: 0374713960
Category: Family & Relationships
Page: 288
View: 3706
A sharp-eyed exploration of the promise and peril of having children in an age of genetic tests and interventions Is screening for disease in an embryo a humane form of family planning or a slippery slope toward eugenics? Should doctors tell you that your infant daughter is genetically predisposed to breast cancer? If tests revealed that your toddler has a genetic mutation whose significance isn’t clear, would you want to know? In The Gene Machine, the award-winning journalist Bonnie Rochman deftly explores these hot-button questions, guiding us through the new frontier of gene technology and how it is transforming medicine, bioethics, health care, and the factors that shape a family. Rochman tells the stories of scientists working to unlock the secrets of the human genome; genetic counselors and spiritual advisers guiding mothers and fathers through life-changing choices; and, of course, parents (including Rochman herself) grappling with revelations that are sometimes joyous, sometimes heartbreaking, but always profound. She navigates the dizzying and constantly expanding array of prenatal and postnatal tests, from carrier screening to genome sequencing, while considering how access to more tests is altering perceptions of disability and changing the conversation about what sort of life is worth living and who draws the line. Along the way, she highlights the most urgent ethical quandary: Is this technology a triumph of modern medicine or a Pandora’s box of possibilities? Propelled by human narratives and meticulously reported, The Gene Machine is both a scientific road map and a meditation on our power to shape the future. It is a book that gets to the very core of what it means to be human.

    • Literary Criticism

The Selfish Gene


Author: Richard Dawkins
Publisher: Oxford University Press, USA
ISBN: 9780192860927
Category: Literary Criticism
Page: 352
View: 9724
An ethologist shows man to be a gene machine whose world is one of savage competition and deceit

    • Science

The Century of the Gene


Author: Evelyn Fox KELLER
Publisher: Harvard University Press
ISBN: 9780674039438
Category: Science
Page: 192
View: 4561

    • Body, Mind & Spirit

The Gene Keys

Unlocking the Higher Purpose Hidden in Your DNA
Author: Richard Rudd
Publisher: Watkins Media Limited
ISBN: 1780286155
Category: Body, Mind & Spirit
Page: 576
View: 2851
The book begins by introducing the reader to a fantastic possibility - that humanity may be on the verge of a major shift in consciousness rooted in a new understanding of how our DNA operates - namely that it is programmed directly by the way we think and feel. This is a highly ambitious and sophisticated system for shaping one's destiny. Based around 64 archetypes, it resembles the I Ching in its vast scope and profound importance, and in the resonant character of its symbolism. The author shows how there are two ways to approach the Gene Keys - the analogue (holistic) way and the digital (detailed) way. It is the combining of both analogue and digital that results in contemplation - the primary pathway into the Gene Keys. Since our beliefs shape our genes, when we change our beliefs, we change the chemistry of our body. The Gene Keys are an inner language whose central purpose is to transform our core beliefs about ourselves, thus raising our lives onto a new level of awareness. The book works alongside state-of-the-art online profiling software. This software will provide instantaneous free profiles known as 'Hologenetic Profiles', which uses astrological data (time, date and place of birth) to generate a unique sequence of Gene Keys that relate to many aspects of your life, including the underlying genetic patterns governing your relationships, your finances, your health and your life purpose. As the reader contemplates the 64 Gene Keys over time and applies their insights in his or her own life, so one's belief system will begin to change and our DNA will actually start to transform the way we think and feel.

    • Nature

In Pursuit of the Gene


Author: James Schwartz
Publisher: Harvard University Press
ISBN: 0674034910
Category: Nature
Page: 384
View: 9763
Ranging from Darwin to the accomplishments of Nobel laureate Hermann J. Muller, a history of genetics as seen through the eyes of a dozen or so central players offers readers the background they need to understand the latest findings in genetics and future trends in the field.

    • Philosophy

The Gene Wars

Science, Politics, and the Human Genome
Author: Robert Cook-Deegan
Publisher: W. W. Norton & Company
ISBN: 9780393313994
Category: Philosophy
Page: 416
View: 7335
The Human Genome Project, the most ambitious biological research program ever undertaken, was born in controversy. Heralded by its more enthusiastic proponents as a quest for the 'Holy Grail of biology' - and the key, ultimately, to the treatment of a variety of hereditary diseases - it has as its initial goal the mapping of all the genes in the entire three-billion-letter genetic code embodied in the DNA of a typical human cell. A major factor in the counterarguments of its opponents: its projected cost, estimated to run into the billions of dollars, spread over 10-20 years. In this firsthand account of the protracted struggle to launch the genome project, a close observer of that process - and sometime participant in it - unravels the tangled scientific and political threads of the story, relying on primary documents gathered even as events unfolded, supplemented by interviews with all the main actors - including the controversial first head of the National Institutes of Health genome effort, Nobel laureate James D. Watson. The result is an absorbing case study in the politics of modern science - focused in this case on a project with far-reaching medical and social implications.

    • Study Aids

Summary and Analysis of The Gene: An Intimate History

Based on the Book by Siddhartha Mukherjee
Author: Worth Books
Publisher: Open Road Media
ISBN: 1504043383
Category: Study Aids
Page: 30
View: 3354
So much to read, so little time? This brief overview of The Gene tells you what you need to know—before or after you read Siddhartha Mukherjee’s book. Crafted and edited with care, Worth Books set the standard for quality and give you the tools you need to be a well-informed reader. This short summary and analysis of The Gene by Siddhartha Mukherjee includes: Historical context Chapter-by-chapter summaries Detailed timeline of key events Important quotes Fascinating trivia Glossary of terms Supporting material to enhance your understanding of the original work About Siddhartha Mukherjee’s The Gene: From the Pulitzer Prize–winning author of The Emperor of All Maladies, The Gene is a rigorously scientific, broadly historical, and candidly personal account of the development of the science of genetics, the dramatic ways genes can affect us, and the enormous moral questions posed by our ability to manipulate them. As Siddhartha Mukherjee maps out the fascinating biography of the gene, from research and experimentation to scientific breakthroughs, he always returns to the narrative of his own family’s tragic history of mental illness, reminding us that despite our huge leaps in knowledge, there is still much we do not understand about the incredibly complex human genome. The Gene is an important read for anyone concerned about a future that may redefine what it means to be human. The summary and analysis in this ebook are intended to complement your reading experience and bring you closer to a great work of nonfiction.

    • Science

p53

The Gene that Cracked the Cancer Code
Author: Sue Armstrong
Publisher: Bloomsbury USA
ISBN: 9781472910516
Category: Science
Page: 288
View: 5830
All of us have lurking in our DNA a most remarkable gene. Its job is to protect us from cancer. This gene-known simply as p53-constantly scans our cells to ensure that when they grow and divide as part of the routine maintenance of our bodies, they do so without mishap. If a cell makes a mistake in copying its DNA during the process of division, p53 stops it in its tracks, sending in the repair team before allowing the cell to carry on dividing. If the mistake is irreparable and the rogue cell threatens to grow out of control (as happens in cancer), p53 commands the cell to commit suicide. Cancer cannot develop unless p53 itself is damaged or handicapped by some other fault in the system. Not surprisingly, p53 is the most studied single gene in history. p53: The Gene that Cracked the Cancer Code tells the story of the discovery of the gene and of medical science's mission to unravel its mysteries and get to the heart of what happens in our cells when they turn cancerous. Through the personal accounts of key researchers, the book reveals the excitement of the hunt for new cures -- the hype, the enthusiasm, the lost opportunities, the blind alleys and the thrilling breakthroughs. As the long-anticipated revolution in cancer treatment tailored to each individual patient's symptoms starts to take off at last, p53 is at the cutting edge. This is a timely tale of scientific discovery and advances in our understanding of a disease that still affects more than one in three of us at some point in our lives.

    • Science

The Gene

From Genetics to Postgenomics
Author: Hans-Jörg Rheinberger,Staffan Müller-Wille
Publisher: University of Chicago Press
ISBN: 022647478X
Category: Science
Page: 176
View: 3409
Few concepts played a more important role in twentieth-century life sciences than that of the gene. Yet at this moment, the field of genetics is undergoing radical conceptual transformation, and some scientists are questioning the very usefulness of the concept of the gene, arguing instead for more systemic perspectives. The time could not be better, therefore, for Hans-Jörg Rheinberger and Staffan Müller-Wille's magisterial history of the concept of the gene. Though the gene has long been the central organizing theme of biology, both conceptually and as an object of study, Rheinberger and Müller-Wille conclude that we have never even had a universally accepted, stable definition of it. Rather, the concept has been in continual flux—a state that, they contend, is typical of historically important and productive scientific concepts. It is that very openness to change and manipulation, the authors argue, that made it so useful: its very mutability enabled it to be useful while the technologies and approaches used to study and theorize about it changed dramatically.

    • Science

The Gene

A Historical Perspective
Author: Ted Everson
Publisher: Greenwood Publishing Group
ISBN: 9780313334498
Category: Science
Page: 188
View: 4573
A history of the science of genetics discusses its roots in heredity, the discovery of DNA, the Human Genome Project, the applications of genetic work, and the controversy surrounding genetic engineering.

    • Medical

The Laws of Medicine

Field Notes from an Uncertain Science
Author: Siddhartha Mukherjee
Publisher: Simon and Schuster
ISBN: 147678485X
Category: Medical
Page: 96
View: 6810
Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.

    • Science

The Gene

by Siddhartha Mukherjee | Summary & Analysis
Author: Instaread
Publisher: Instaread
ISBN: 1683783700
Category: Science
Page: 42
View: 5660
The Gene by Siddhartha Mukherjee | Summary & Analysis Preview: The Gene by Siddhartha Mukherjee describes the history of genetic research, the impact of genetic inheritance on his family, and the potential for future applications of gene science. Mukherjee’s father and uncles struggled with disorders such as schizophrenia and bipolar disorder, both of which are linked to genetic mutations. After centuries of conjecture about the nature of familial inheritance, naturalist Charles Darwin published his theory of evolution in 1859. In 1865, botanist Gregor Mendel proposed that genetic information is passed down from both the paternal and maternal sides of the family in the form of paired genes. Thereafter, eugenics gradually became socially accepted and programs to sterilize the disabled and deviant were established in the United States. The practice of eugenics became socially abhorrent following World War II and the revelations of genocidal practices in Nazi Germany and Stalinist Russia. Between 1908 and 1963, scientists continued studying genetic material… PLEASE NOTE: This is key takeaways and analysis of the book and NOT the original book. Inside this Instaread Summary of The Gene · Overview of the Book · Important People · Key Takeaways · Analysis of Key Takeaways The Gene by Siddhartha Mukherjee | Summary & Analysis Preview: The Gene by Siddhartha Mukherjee describes the history of genetic research, the impact of genetic inheritance on his family, and the potential for future applications of gene science. Mukherjee’s father and uncles struggled with disorders such as schizophrenia and bipolar disorder, both of which are linked to genetic mutations. After centuries of conjecture about the nature of familial inheritance, naturalist Charles Darwin published his theory of evolution in 1859. In 1865, botanist Gregor Mendel proposed that genetic information is passed down from both the paternal and maternal sides of the family in the form of paired genes. Thereafter, eugenics gradually became socially accepted and programs to sterilize the disabled and deviant were established in the United States. The practice of eugenics became socially abhorrent following World War II and the revelations of genocidal practices in Nazi Germany and Stalinist Russia. Between 1908 and 1963, scientists continued studying genetic material… PLEASE NOTE: This is key takeaways and analysis of the book and NOT the original book. Inside this Instaread Summary of The Gene: · Overview of the Book · Important People · Key Takeaways · Analysis of Key Takeaways About the Author With Instaread, you can get the key takeaways, summary and analysis of a book in 15 minutes. We read every chapter, identify the key takeaways and analyze them for your convenience.

    • Sports & Recreation

The Sports Gene

Inside the Science of Extraordinary Athletic Performance
Author: David Epstein
Publisher: Penguin
ISBN: 1101622636
Category: Sports & Recreation
Page: 352
View: 5683
The New York Times bestseller – with a new afterword about early specialization in youth sports. The debate is as old as physical competition. Are stars like Usain Bolt, Michael Phelps, and Serena Williams genetic freaks put on Earth to dominate their respective sports? Or are they simply normal people who overcame their biological limits through sheer force of will and obsessive training? In this controversial and engaging exploration of athletic success and the so-called 10,000-hour rule, David Epstein tackles the great nature vs. nurture debate and traces how far science has come in solving it. Through on-the-ground reporting from below the equator and above the Arctic Circle, revealing conversations with leading scientists and Olympic champions, and interviews with athletes who have rare genetic mutations or physical traits, Epstein forces us to rethink the very nature of athleticism.

The Extended Phenotype

The Long Reach of the Gene
Author: Richard Dawkins
Publisher: Oxford University Press
ISBN: 0198788916
Category:
Page: 496
View: 7201
In The Selfish Gene, Richard Dawkins crystallized the gene's eye view of evolution developed by W.D. Hamilton and others. The book provoked widespread and heated debate. Written in part as a response, The Extended Phenotype gave a deeper clarification of the central concept of the gene as theunit of selection; but it did much more besides. In it, Dawkins extended the gene's eye view to argue that the genes that sit within an organism have an influence that reaches out beyond the visible traits in that body - the phenotype - to the wider environment, which can include other individuals.So, for instance, the genes of the beaver drive it to gather twigs to produce the substantial physical structure of a dam; and the genes of the cuckoo chick produce effects that manipulate the behaviour of the host bird, making it nurture the intruder as one of its own. This notion of the extendedphenotype has proved to be highly influential in the way we understand evolution and the natural world. It represents a key scientific contribution to evolutionary biology, and it continues to play an important role in research in the life sciences.The Extended Phenotype is a conceptually deep book that forms important reading for biologists and students. But Dawkins' clear exposition is accessible to all who are prepared to put in a little effort.Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.

    • Cooking for the sick

The Gene Therapy Plan

Taking Control of Your Genetic Destiny with Diet and Lifestyle
Author: Mitchell L. Gaynor
Publisher: Penguin Books
ISBN: 0143108190
Category: Cooking for the sick
Page: 346
View: 3498
Renowned physician Dr. Gaynor believes we are capable of changing our genetic destiny by changing the habits that affect our good and bad genes. His revolutionary approach focuses on obesity, heart disease, diabetes, cancer and aging to explain what we can do to keep our bodies on their natural path toward healthy, balanced functioning. Here he presents the science behind these ideas and provides plans and recipes to help put them into practice. Empowering and informative, this meticulously researched book offers accessible ways to tranform our health.

    • Medical

The Missing Gene

Psychiatry, Heredity, and the Fruitless Search for Genes
Author: Jay Joseph
Publisher: Algora Publishing
ISBN: 0875864112
Category: Medical
Page: 324
View: 3033
Researchers still haven't found the genes that underlie schizophrenia, bipolar disorder, ADHD, and autism; perhaps they do not exist. A genetic researcher in psychiatry and psychology urges we return our focus to family, social, and political environments as the sources of psychological distress.

    • Biography & Autobiography

Gene Machine

The Race to Decipher the Secrets of the Ribosome
Author: Venki Ramakrishnan
Publisher: Basic Books
ISBN: 046509337X
Category: Biography & Autobiography
Page: 288
View: 2669
A Nobel Prize-winning biologist tells the riveting story of his race to discover the inner workings of biology's most important molecule "Ramakrishnan's writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end."--Siddhartha Mukherjee, author of The Emperor of All Maladies and The Gene Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.