• Mathematics

When Topology Meets Chemistry

A Topological Look at Molecular Chirality
Author: Erica Flapan
Publisher: Cambridge University Press
ISBN: 9780521664820
Category: Mathematics
Page: 241
View: 1956
An undergraduate topology text describing knot theory, 3-dimensional manifolds, and embedded graphs, and the role these play in understanding molecular structures.

    • Algebraic topology

Knots, Molecules, and the Universe


Author: Erica Flapan
Publisher: American Mathematical Soc.
ISBN: 1470425351
Category: Algebraic topology
Page: 386
View: 8575
This book is an elementary introduction to geometric topology and its applications to chemistry, molecular biology, and cosmology. It does not assume any mathematical or scientific background, sophistication, or even motivation to study mathematics. It is meant to be fun and engaging while drawing students in to learn about fundamental topological and geometric ideas. Though the book can be read and enjoyed by nonmathematicians, college students, or even eager high school students, it is intended to be used as an undergraduate textbook. The book is divided into three parts corresponding to the three areas referred to in the title. Part 1 develops techniques that enable two- and three-dimensional creatures to visualize possible shapes for their universe and to use topological and geometric properties to distinguish one such space from another. Part 2 is an introduction to knot theory with an emphasis on invariants. Part 3 presents applications of topology and geometry to molecular symmetries, DNA, and proteins. Each chapter ends with exercises that allow for better understanding of the material. The style of the book is informal and lively. Though all of the definitions and theorems are explicitly stated, they are given in an intuitive rather than a rigorous form, with several hundreds of figures illustrating the exposition. This allows students to develop intuition about topology and geometry without getting bogged down in technical details.

    • Science

The Role of Topology in Materials


Author: Sanju Gupta,Avadh Saxena
Publisher: Springer
ISBN: 3319765965
Category: Science
Page: 297
View: 7381
This book presents the most important advances in the class of topological materials and discusses the topological characterization, modeling and metrology of materials. Further, it addresses currently emerging characterization techniques such as optical and acoustic, vibrational spectroscopy (Brillouin, infrared, Raman), electronic, magnetic, fluorescence correlation imaging, laser lithography, small angle X-ray and neutron scattering and other techniques, including site-selective nanoprobes. The book analyzes the topological aspects to identify and quantify these effects in terms of topology metrics. The topological materials are ubiquitous and range from (i) de novo nanoscale allotropes of carbons in various forms such as nanotubes, nanorings, nanohorns, nanowalls, peapods, graphene, etc. to (ii) metallo-organic frameworks, (iii) helical gold nanotubes, (iv) Möbius conjugated polymers, (v) block co-polymers, (vi) supramolecular assemblies, to (vii) a variety of biological and soft-matter systems, e.g. foams and cellular materials, vesicles of different shapes and genera, biomimetic membranes, and filaments, (viii) topological insulators and topological superconductors, (ix) a variety of Dirac materials including Dirac and Weyl semimetals, as well as (x) knots and network structures. Topological databases and algorithms to model such materials have been also established in this book. In order to understand and properly characterize these important emergent materials, it is necessary to go far beyond the traditional paradigm of microscopic structure–property–function relationships to a paradigm that explicitly incorporates topological aspects from the outset to characterize and/or predict the physical properties and currently untapped functionalities of these advanced materials. Simulation and modeling tools including quantum chemistry, molecular dynamics, 3D visualization and tomography are also indispensable. These concepts have found applications in condensed matter physics, materials science and engineering, physical chemistry and biophysics, and the various topics covered in the book have potential applications in connection with novel synthesis techniques, sensing and catalysis. As such, the book offers a unique resource for graduate students and researchers alike.

    • Self-Help

40 Days of Dating

An Experiment
Author: Timothy Goodman,Jessica Walsh
Publisher: ABRAMS
ISBN: 1613127154
Category: Self-Help
Page: 304
View: 7186
“What would happen if Harry met Sally in the age of Tinder and Snapchat? . . . A field guide to Millennial dating in New York City” (New York Daily News). When New York–based graphic designers and long-time friends Timothy Goodman and Jessica Walsh found themselves single at the same time, they decided to try an experiment. The old adage says that it takes 40 days to change a habit—could the same be said for love? So they agreed to date each other for 40 days, record their experiences in questionnaires, photographs, videos, texts, and artworks, and post the material on a website they would create for this purpose. What began as a small experiment between two friends became an Internet sensation, drawing 5 million unique (and obsessed) visitors from around the globe to their site and their story. 40 Days of Dating: An Experiment is a beautifully designed, expanded look at the experiment and the results, including a great deal of material that never made it onto the site, such as who they were as friends and individuals before the 40 days and who they have become since.

    • Technology & Engineering

Engineering of Crystalline Materials Properties

State of the Art in Modeling, Design and Applications
Author: Juan J. Novoa,Dario Braga,Lia Addadi
Publisher: Springer Science & Business Media
ISBN: 9781402068232
Category: Technology & Engineering
Page: 518
View: 9572
This volume collects the state of the art in molecular materials. It collects the lecture notes of a series of lectures given by some of the best specialists in the field at the 2007 Erice International School of Crystallography, and also a NATO-ASI course. The school first established "where we are" in terms of modeling, design, synthesis and applications of crystalline solids with predefined properties and then defined current and possible futuristic lines of development.

    • Science

Inorganic Chemical Biology

Principles, Techniques and Applications
Author: Gilles Gasser
Publisher: John Wiley & Sons
ISBN: 111868415X
Category: Science
Page: 432
View: 8252
Understanding, identifying and influencing the biological systems are the primary objectives of chemical biology. From this perspective, metal complexes have always been of great assistance to chemical biologists, for example, in structural identification and purification of essential biomolecules, for visualizing cellular organelles or to inhibit specific enzymes. This inorganic side of chemical biology, which continues to receive considerable attention, is referred to as inorganic chemical biology. Inorganic Chemical Biology: Principles, Techniques and Applications provides a comprehensive overview of the current and emerging role of metal complexes in chemical biology. Throughout all of the chapters there is a strong emphasis on fundamental theoretical chemistry and experiments that have been carried out in living cells or organisms. Outlooks for the future applications of metal complexes in chemical biology are also discussed. Topics covered include: • Metal complexes as tools for structural biology • IMAC, AAS, XRF and MS as detection techniques for metals in chemical biology • Cell and organism imaging and probing DNA using metal and metal carbonyl complexes • Detection of metal ions, anions and small molecules using metal complexes • Photo-release of metal ions in living cells • Metal complexes as enzyme inhibitors and catalysts in living cells Written by a team of international experts, Inorganic Chemical Biology: Principles, Techniques and Applications is a must-have for bioinorganic, bioorganometallic and medicinal chemists as well as chemical biologists working in both academia and industry.

    • Mathematics

Developments in Language Theory

8th International Conference, DLT 2004, Auckland, New Zealand, December 13-17, Proceedings
Author: Cristian S. Calude,Elena Calude,Michael J. Dinneen
Publisher: Springer
ISBN: 3540305505
Category: Mathematics
Page: 436
View: 1323

    • Science

Macrocyclic Chemistry

Current Trends and Future Perspectives
Author: K. Gloe
Publisher: Springer Science & Business Media
ISBN: 1402036876
Category: Science
Page: 450
View: 8114
Macrocyclic Chemistry: Current Trends and Future Perspectives illustrates essential concepts in this expanding research field covering both basic and applied studies. Written by well-known experts from around the world, the topics of the chapters range from new macrocyclic architectures with different functions and self-assembly processes through to the modeling and dynamics of such systems. The content also reflects on application possibilities in analytical chemistry, separation processes, material preparation and medicine. Thus this book serves as a creative source of research strategies and methodic tools. Providing an excellent overview of the field, this book will be a valuable resource for researchers in industry and academic institutions as well as for teachers of science and graduate students. This book is devoted to the long-standing tradition of the International Symposia on Macrocyclic Chemistry (ISMC) and published to coincide with the 30th meeting, Dresden, Germany.

    • Science

Biochirality

Origins, Evolution and Molecular Recognition
Author: Pedro Cintas
Publisher: Springer
ISBN: 3642376266
Category: Science
Page: 316
View: 4204
Early History of the Recognition of Molecular Biochirality, by Joseph Gal, Pedro Cintas Synthesis and Chirality of Amino Acids Under Interstellar Conditions, by Chaitanya Giri, Fred Goesmann, Cornelia Meinert, Amanda C. Evans, Uwe J. Meierhenrich Chemical and Physical Models for the Emergence of Biological Homochirality, by son E. Hein, Dragos Gherase, Donna G. Blackmond Biomolecules at Interfaces: Chiral, Naturally, by Arántzazu González-Campo and David B. Amabilino Stochastic Mirror Symmetry Breaking: Theoretical Models and Simulation of Experiments, by Celia Blanco, David Hochberg Self-Assembly of Dendritic Dipeptides as a Model of Chiral Selection in Primitive Biological Systems, by Brad M. Rosen, Cécile Roche, Virgil Percec Chirality and Protein Biosynthesis, by Sindrila Dutta Banik, Nilashis Nandi

    • Science

Chemical Synthesis

Gnosis to Prognosis
Author: C. Chatgilialoglu,V. Snieckus
Publisher: Springer Science & Business Media
ISBN: 9400902557
Category: Science
Page: 625
View: 1455
Chemical Synthesis: Gnosis to Prognosis (XTUllKtl ~uv8eoTr ana TT) rVWOT) OTT) npaYVWOT)) " . . . . other things being equal, that field has the most merit which contributes most heavily to, and illuminates most brightly, its neighbouring scientific disciplines[l] One hundred scientists, a blend of students, industrialists, and academics from twenty countries gathered to circumscribe, understand, and elaborate this topic in the magical setting of Ravello, Italy. The mandate of this workshop? To survey existing knowledge, assess current work, and discuss the future directions of chemical synthesis as it impinges on three exciting interdisciplinary themes of science in the 1990's: bioactive molecules, man-made chemical materials, and molecular recognition. This tempting but inexact menu summoned diverse students and scientists who wished to seriously reflect upon, dissect, and eject ideas and own experiences into open debate on this topic, which is at a crossroad in internal evolution and impact on the life and material sciences. The group arrived from many directions and in various forms of transportation, matters soon forgotten, when it found itself in the village which nurtured Wagner's inspiration and set to work immediately to ponder the question which has received extensive thought, prediction, and caveat from illustrious chemists over a period of time [2], two of which, to the delight of all, in presence among the Lectures.

    • Mathematics

Applications of Knot Theory

American Mathematical Society, Short Course, January 4-5, 2008, San Diego, California
Author: American Mathematical Society. Short course,Dorothy Buck
Publisher: American Mathematical Soc.
ISBN: 0821844660
Category: Mathematics
Page: 186
View: 9539
Over the past 20-30 years, knot theory has rekindled its historic ties with biology, chemistry, and physics as a means of creating more sophisticated descriptions of the entanglements and properties of natural phenomena--from strings to organic compounds to DNA. This volume is based on the 2008 AMS Short Course, Applications of Knot Theory. The aim of the Short Course and this volume, while not covering all aspects of applied knot theory, is to provide the reader with a mathematical appetizer, in order to stimulate the mathematical appetite for further study of this exciting field. No prior knowledge of topology, biology, chemistry, or physics is assumed. In particular, the first three chapters of this volume introduce the reader to knot theory (by Colin Adams), topological chirality and molecular symmetry (by Erica Flapan), and DNA topology (by Dorothy Buck). The second half of this volume is focused on three particular applications of knot theory. Louis Kauffman discusses applications of knot theory to physics, Nadrian Seeman discusses how topology is used in DNA nanotechnology, and Jonathan Simon discusses the statistical and energetic properties of knots and their relation to molecular biology.

    • Science

Chemistry of Zeolites and Related Porous Materials

Synthesis and Structure
Author: Ruren Xu,Wenqin Pang,Jihong Yu,Qisheng Huo,Jiesheng Chen
Publisher: John Wiley & Sons
ISBN: 9780470822364
Category: Science
Page: 616
View: 3348
Widely used in adsorption, catalysis and ion exchange, the family of molecular sieves such as zeolites has been greatly extended and many advances have recently been achieved in the field of molecular sieves synthesis and related porous materials. Chemistry of Zeolites and Related Porous Materials focuses on the synthetic and structural chemistry of the major types of molecular sieves. It offers a systematic introduction to and an in-depth discussion of microporous, mesoporous, and macroporous materials and also includes metal-organic frameworks. Provides focused coverage of the key aspects of molecular sieves Features two frontier subjects: molecular engineering and host-guest advanced materials Comprehensively covers both theory and application with particular emphasis on industrial uses This book is essential reading for researches in the chemical and materials industries and research institutions. The book is also indispensable for researches and engineers in R&D (for catalysis) divisions of companies in petroleum refining and the petrochemical and fine chemical industries.

    • Science

NanoBioTechnology

BioInspired Devices and Materials of the Future
Author: Oded Shoseyov,Ilan Levy
Publisher: Springer Science & Business Media
ISBN: 9781597452182
Category: Science
Page: 485
View: 569
NanoBiotechnology is a groundbreaking text investigating the recent advances and future direction of nanobiotechnology. It will assist scientists and students in learning the fundamentals and cutting-edge nature of this new and emerging science. Focusing on materials and building blocks for nanotechnology, leading scientists from around the world share their knowledge and expertise in this authoritative volume.

    • Science

Cosmological Physics


Author: J. A. Peacock
Publisher: Cambridge University Press
ISBN: 9780521422703
Category: Science
Page: 682
View: 1339
An eagerly-awaited, comprehensive and authoritative introduction to contemporary cosmology; for advanced undergraduate and graduate students.

    • Technology & Engineering

Synthesis and Applications of Copolymers


Author: Anbanandam Parthiban
Publisher: John Wiley & Sons
ISBN: 1118860489
Category: Technology & Engineering
Page: 400
View: 1293
Understanding the reactivity of monomers is crucial in creating copolymers and determining the outcome of copolymerization. Covering the fundamental aspects of polymerization, Synthesis and Applications of Copolymers explores the reactivity of monomers and reaction conditions that ensure that the newly formed polymeric materials exhibit desired properties. Referencing a wide-range of disciplines, the book provides researchers, students, and scientists with the preparation of a diverse variety of copolymers and their recent developments, with a particular focus on copolymerization, crystallization, and techniques like nanoimprinting and micropatterning.

    • Science

Recent Advances in QSAR Studies

Methods and Applications
Author: Tomasz Puzyn,Jerzy Leszczynski,Mark T. Cronin
Publisher: Springer Science & Business Media
ISBN: 9781402097836
Category: Science
Page: 414
View: 9596
This book presents an interdisciplinary overview on the most recent advances in QSAR studies. The first part consists of a comprehensive review of QSAR methodology. The second part highlights the interdisciplinary aspects and new areas of QSAR modelling.

    • Science

Advances in QSAR modeling

Applications in Pharmaceutical, Chemical, Food, Agricultural and Environmental Sciences
Author: Kunal Roy
Publisher: Springer
ISBN: 3319568507
Category: Science
Page: 555
View: 2506
The book covers theoretical background and methodology as well as all current applications of Quantitative Structure-Activity Relationships (QSAR). Written by an international group of recognized researchers, this edited volume discusses applications of QSAR in multiple disciplines such as chemistry, pharmacy, environmental and agricultural sciences addressing data gaps and modern regulatory requirements. Additionally, the applications of QSAR in food science and nanoscience have been included – two areas which have only recently been able to exploit this versatile tool. This timely addition to the series is aimed at graduate students, academics and industrial scientists interested in the latest advances and applications of QSAR.

    • Technology & Engineering

Biosensors Nanotechnology


Author: Ashutosh Tiwari,Anthony P. F. Turner
Publisher: John Wiley & Sons
ISBN: 1118773810
Category: Technology & Engineering
Page: 552
View: 1999
This book provides detailed reviews of a range of nanostructures used in the construction of biosensors as well as the applications of these biosensor nanotechnologies in the biological, chemical, and environmental monitoring fields Biological sensing is a fundamental tool for understanding living systems, but also finds practical application in medicine, drug discovery, process control, food safety, environmental monitoring, defense, and personal security. Moreover, a deeper understanding of the bio/electronic interface leads us towards new horizons in areas such as bionics, power generation, and computing. Advances in telecommunications, expert systems, and distributed diagnostics prompt us to question the current ways we deliver healthcare, while robust industrial sensors enable new paradigms in R&D and production. Despite these advances, there is a glaring absence of suitably robust and convenient sensors for body chemistries. This book examines some of the emerging technologies that are fueling scientific discovery and underpinning new products to enhance the length and quality of our lives. The 14 chapters written by leading experts cover such topics as: ZnO and graphene microelectrode applications in biosensing Assembly of polymers/metal nanoparticles Gold nanoparticle-based electrochemical biosensors Impedimetric DNA sensing employing nanomaterials Graphene and carbon nanotube-based biosensors Computational nanochemistry study of the BFPF green fluorescent protein chromophore Biosynthesis of metal nanoparticles Bioconjugated-nanoporous gold films in electrochemical biosensors The combination of molecular imprinting and nanotechnology Principles and properties of multiferroics and ceramics

    • Science

Symmetry 2

Unifying Human Understanding
Author: I. Hargittai
Publisher: Elsevier
ISBN: 148329949X
Category: Science
Page: 1084
View: 6967
Symmetry 2 aims to present an overview of the contemporary status of symmetry studies, particularly in the arts and sciences, emphasizing both its role and importance. Symmetry is not only one of the fundamental concepts in science, but is also possibly the best unifying concept between various branches of science, the arts and other human activities. Whereas symmetry has been considered important for centuries primarily for its aesthetic appeal, this century has witnessed a dramatic enhancement of its status as a cornerstone in the sciences. In addition to traditionally symmetry-oriented fields such as crystallography and spectroscopy, the concept has made headway in fields as varied as reaction chemistry, nuclear physics, and the study of the origin of the universe. The book was initiated in response to the success of the first volume, which not only received good reviews, but received the award for "The Best Single Issue of a Journal" by the Association of American Publishers for 1986. The second volume extends the application of symmetry to new fields, such as medical sciences and economics, as well as investigating further certain topics introduced in Symmetry. The book is extensively illustrated and with over 64 contributions from 16 countries presents an international overview of the nature and diversity of symmetry studies today.

    • Science

Small Molecule Medicinal Chemistry

Strategies and Technologies
Author: Werngard Czechtizky,Peter Hamley
Publisher: John Wiley & Sons
ISBN: 1118771575
Category: Science
Page: 528
View: 5104
Stressing strategic and technological solutions to medicinal chemistry challenges, this book presents methods and practices for optimizing the chemical aspects of drug discovery. Chapters discuss benefits, challenges, case studies, and industry perspectives for improving drug discovery programs with respect to quality and costs. • Focuses on small molecules and their critical role in medicinal chemistry, reviewing chemical and economic advantages, challenges, and trends in the field from industry perspectives • Discusses novel approaches and key topics, like screening collection enhancement, risk sharing, HTS triage, new lead finding approaches, diversity-oriented synthesis, peptidomimetics, natural products, and high throughput medicinal chemistry approaches • Explains how to reduce design-make-test cycle times by integrating medicinal chemistry, physical chemistry, and ADME profiling techniques • Includes descriptive case studies, examples, and applications to illustrate new technologies and provide step-by-step explanations to enable them in a laboratory setting